Lipoic acid (LA), also known as α-lipoic acid and alpha lipoic acid (ALA) and thioctic acid is an organosulfur compound derived from octanoic acid. ALA is made in animals normally, and is essential for aerobic metabolism. It is also manufactured and is available as a dietary supplement in some countries where it is marketed as an antioxidant, and is available as a pharmaceutical drug in other countries.
INVENTORY COUNT (kgs) : 0.5kg
Starting at
IUPAC name
(R)-5-(1,2-Dithiolan-3-yl)pentanoic acid
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Other names
α-Lipoic acid; Alpha lipoic acid; Thioctic acid; 6,8-Dithiooctanoic acid
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CAS Number | 1200-22-2 (R) 1077-28-7 (racemate) |
ChEBI | CHEBI:30314 |
ChEMBL | ChEMBL134342 |
ChemSpider | 5886 |
DrugBank | DB00166 |
IUPHAR/BPS | 4822 |
Jmol interactive 3D | Image |
KEGG | C16241 |
MeSH | Lipoic+acid |
PubChem | 6112 |
UNII | VLL71EBS9Z |
InChI[show] | |
SMILES[show] |
Chemical formula
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C8H14O2S2 |
Molar mass | 206.32 g·mol−1 |
Appearance | Yellow needle-like crystals |
Melting point | 46–48 °C (115–118 °F; 319–321 K) |
Solubility in water
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Soluble as sodium salt |
Solubility in ethanol | Soluble |
ATC code | A16AX01 |
Pharmacokinetics: | |
Bioavailability
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30% (oral)[1] |
Related compounds
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Lipoamide Asparagusic acid |