Ampicillin is an antibiotic used to prevent and treat a number of bacterial infections.[2] This includes respiratory tract infections, urinary tract infections, meningitis, salmonella infections, and endocarditis. It may also be used to prevent group B streptococcal infection in newborns. It is used by mouth, by injection into a muscle, or intravenously.[2] It is not useful for the treatment of viral infections.
Starting at
(2S,5R,6R)-6-([(2R)-2-amino-2-phenylacetyl]amino) -3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid |
Trade names | Principen, others[1] |
AHFS/Drugs.com | monograph |
MedlinePlus | a685002 |
Licence data | US FDA:link |
Pregnancy category | A (Au), B (U.S.) |
Legal status | UK: POM (Prescription only) |
Routes of administration | By mouth, intravenous |
Bioavailability | 40% (oral) |
Protein binding | 15 to 25% |
Metabolism | 12 to 50% |
Biological half-life | approx 1 hour |
Excretion | 75 to 85% renal |
CAS Number | 69-53-4 |
ATC code | J01CA01 S01AA19 QJ51CA01 |
PubChem | CID: 6249 |
DrugBank | DB00415 |
ChemSpider | 6013 |
UNII | 7C782967RD |
KEGG | D00204 |
ChEBI | CHEBI:28971 |
ChEMBL | CHEMBL174 |
Formula | C16H19N3O4S |
Molecular mass | 349.41 g·mol−1 |
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InChI[show] |