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colistin-sulfate

Colistin Sulfate

Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Paenibacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic.

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Product Description


N-(4-amino-1-(1-(4-amino-1-oxo-1-(3,12,23-tris(2-aminoethyl)- 20-(1-hydroxyethyl)-6,9-diisobutyl-2,5,8,11,14,19,22-heptaoxo- 1,4,7,10,13,18-hexaazacyclotricosan-15-ylamino)butan-2-ylamino)- 3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-N,5-dimethylheptanamide

Trade names Coly-mycinm; Coly-monas(India)
Pregnancy
category
C
Legal status PoM (UK), not available in US
Routes of
administration
topical, oral, intravenous, inhaled

Bioavailability 0%
Biological half-life 5 hours

CAS Number 1264-72-8
ATC code A07AA10 J01XB01 QJ51XB01
PubChem CID: 5311054
DrugBank DB00803
ChemSpider 4470591
UNII WP15DXU577
KEGG D02138
ChEMBL CHEMBL501505

Formula C52H98N16O13
Molecular mass 1155.4495 g/mol
SMILES[show]
InChI[show]