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doxazosin-mesylate

Doxazosin Mesylate

Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand names Cardura and Carduran, is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia (BPH).

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Product Description


(RS)-2-[4-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine

Trade names Cardura
AHFS/Drugs.com monograph
MedlinePlus a693045
Legal status ℞ (Prescription only)
Routes of
administration
oral

Bioavailability 65%
Protein binding 98%
Metabolism Hepatic
Biological half-life 22 hours

CAS Number 74191-85-8
ATC code C02CA04
PubChem CID: 3157
IUPHAR/BPS 7170
DrugBank DB00590
ChemSpider 3045
UNII NW1291F1W8
KEGG D07874
ChEBI CHEBI:4708
ChEMBL CHEMBL707

Formula C23H25N5O5
Molecular mass 451.475 g/mol
SMILES[show]
InChI[show]