Hyoscine butylbromide, also known as scopolamine butylbromide[1] and sold under the brandname Buscopan,[2] is a medication used to treat crampy abdominal pain, renal colic, and bladder spasms.[2][3] It is also used to improve a death rattle at the end of life.[4] Hyoscine butylbromide can be taken by mouth, injection into a muscle, or into a vein.[2]
Starting at
[7(S)-(1α,2β,4β,5α,7β)]-9-butyl-7-(3-hydroxy- 1-oxo-2-phenylpropoxy)-9-methyl-3-oxa- 9-azonitricyclo[3.3.1.0(2,4)]nonane |
Trade names | Buscopan |
Pregnancy category |
AU: B2 |
Legal status |
AU : S2 (Pharmacy only) UK : General sales list (GSL, OTC) |
Routes of administration |
Oral, rectal, intravenous |
Bioavailability | <1% |
Protein binding | Low |
Biological half-life | 5 hours |
Excretion | Renal (50%)[citation needed] and fecal |
CAS Number | 149-64-4 |
ATC code | A03BB01 |
PubChem | CID: 160883 |
DrugBank | DB09300 |
ChemSpider | 16736107 |
UNII | 2Z3E1OF81V |
ChEMBL | CHEMBL1256901 |
Formula | C21H30NO4+ |
Molecular mass | 360.467 g/mol |
SMILES[show] | |
InChI[show] |