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Butylscopolamine_skeletal

Hyoscine butylbromide (Scopolamine)

Hyoscine butylbromide, also known as scopolamine butylbromide[1] and sold under the brandname Buscopan,[2] is a medication used to treat crampy abdominal pain, renal colic, and bladder spasms.[2][3] It is also used to improve a death rattle at the end of life.[4] Hyoscine butylbromide can be taken by mouth, injection into a muscle, or into a vein.[2]

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Product Description


[7(S)-(1α,2β,4β,5α,7β)]-9-butyl-7-(3-hydroxy-
1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-
9-azonitricyclo[3.3.1.0(2,4)]nonane

Trade names Buscopan
Pregnancy
category
AU: B2
Legal status AU : S2 (Pharmacy only)
UK : General sales list (GSL, OTC)
Routes of
administration
Oral, rectal, intravenous

Bioavailability <1%
Protein binding Low
Biological half-life 5 hours
Excretion Renal (50%)[citation needed] and fecal

CAS Number 149-64-4
ATC code A03BB01
PubChem CID: 160883
DrugBank DB09300
ChemSpider 16736107
UNII 2Z3E1OF81V
ChEMBL CHEMBL1256901

Formula C21H30NO4+
Molecular mass 360.467 g/mol
SMILES[show]
InChI[show]