Ivermectin
Ivermectin is a medication that is effective against many types of parasites.[1] It is used to treat head lice,[2] scabies,[3] river blindness,[4] strongyloidiasis,[5] and lymphatic filariasis, among others.[6] It can be either applied to the skin or taken by mouth. The eyes should be avoided.[2]
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Product Description
| 22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b |
| Trade names | Stromectol |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a607069 |
| Pregnancy category |
AU: B3 US: C (Risk not ruled out) |
| Legal status | US: ℞-only |
| Routes of administration |
Oral, topical |
| Protein binding | 93% |
| Metabolism | Liver (CYP450) |
| Biological half-life | 18 hours |
| Excretion | Feces; <1% urine |
| CAS Number | 70288-86-7 71827-03-7 |
| ATC code | D11AX22 P02CF01 QP54AA01 QS02QA03 |
| PubChem | CID: 9812710 |
| DrugBank | DB00602 |
| ChemSpider | 7988461 |
| UNII | 8883YP2R6D |
| KEGG | D00804 |
| ChEMBL | CHEMBL341047 |
| PDB ligand ID | IVM (PDBe, RCSB PDB) |
| Formula | C 48H 74O 14 (22,23-dihydroavermectin B1a) C 47H 72O 14 (22,23-dihydroavermectin B1b) |
| Molecular mass | 875.10 g/mol |
| InChI[show] | |
