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histidine

L-Histidine

Histidine (abbreviated as His or H; encoded by the codons CAU and CAC) is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated –+NH3 form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO- form under biological conditions), and a side chain imidazole, classifying it as a positively charged (at physiological pH), aromatic amino acid. Initially thought essential only for infants, longer-term studies shown it is essential for adults also.[2]

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Product Description


IUPAC name

Histidine
Other names

2-Amino-3-(1H-imidazol-4-yl)propanoic acid

CAS Number
71-00-1
ChEBI CHEBI:57595
ChEMBL ChEMBL17962
ChemSpider 6038
DrugBank DB00117
IUPHAR/BPS
3310
Jmol interactive 3D Image
Image
KEGG D00032
PubChem 773
UNII 4QD397987E
InChI[show]
SMILES[show]

Chemical formula
C6H9N3O2
Molar mass 155.16 g·mol−1
Solubility in water
4.19g/100g @ 25 °C [1]

Safety data sheet See: data page
NFPA 704

Structure and
properties
Refractive index (n),
Dielectric constant (εr), etc.
Thermodynamic
data
Phase behaviour
solid–liquid–gas
Spectral data
UV, IR, NMR, MS