Lincomycin is a lincosamide antibiotic that comes from the actinomyces Streptomyces lincolnensis.[1] A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality.[2]
Starting at
(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
|
AHFS/Drugs.com | monograph |
MedlinePlus | a609005 |
Pregnancy category |
US : C (Risk not ruled out) |
Legal status | US: ℞-only |
Routes of administration |
IM/IV |
Bioavailability | N/A |
---|---|
Biological half-life | 5.4 ± 1.0 hours after IM or IV administration |
Excretion | renal and biliary |
CAS Number | 154-21-2 |
ATC code | J01FF02 |
PubChem | CID: 3000540 |
DrugBank | DB01627 |
ChemSpider | 2272112 |
UNII | BOD072YW0F |
KEGG | D00223 |
ChEBI | CHEBI:6472 |
ChEMBL | CHEMBL1447 |