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Lincomycin

Lincomycin Hcl

Lincomycin is a lincosamide antibiotic that comes from the actinomyces Streptomyces lincolnensis.[1] A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality.[2]

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Product Description


(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide

AHFS/Drugs.com monograph
MedlinePlus a609005
Pregnancy
category
US : C (Risk not ruled out)
Legal status US: ℞-only
Routes of
administration
IM/IV

Bioavailability N/A
Biological half-life 5.4 ± 1.0 hours after IM or IV administration
Excretion renal and biliary

CAS Number 154-21-2
ATC code J01FF02
PubChem CID: 3000540
DrugBank DB01627
ChemSpider 2272112
UNII BOD072YW0F
KEGG D00223
ChEBI CHEBI:6472
ChEMBL CHEMBL1447

Formula C18H34N2O6S Molecular mass 406.538 g/mol SMILES[show] InChI[show]