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metoclopramide-hcl

Metoclopramide Hcl

Metoclopramide is a medication used mostly for stomach and esophageal problems.[1] It is commonly used to treat nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying due to either diabetes or following surgery, and to help with gastroesophageal reflux disease.[2] It is also used to treat migraine headaches.[3]

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Product Description


Systematic (IUPAC) name
4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

Pronunciation /ˌmɛtəˈklɒprəmaɪd/
Trade names list
AHFS/Drugs.com monograph
MedlinePlus a684035
Licence data US FDA:link
Pregnancy
category
AU: A
US: B (No risk in non-human studies)
Legal status AU: S4 (Prescription only)
UK: POM (Prescription only)
US: ℞-only
Routes of
administration
Oral, intravenous, intramuscular

Bioavailability 80±15% (oral)
Metabolism Hepatic
Biological half-life 5–6 hours
Excretion 70–85% renal, 2% faecal

CAS Number 364-62-5
ATC code A03FA01
PubChem CID: 4168
IUPHAR/BPS 241
DrugBank DB01233
ChemSpider 4024
UNII L4YEB44I46
KEGG D00726
ChEBI CHEBI:107736
ChEMBL CHEMBL86

Formula C14H22ClN3O2
Molecular mass 299.80 g/mol

SMILES[show]

InChI[show]

Melting point 147.3 °C (297.1 °F)