Neomycin Sulphate
Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. The discovery of neomycin dates back to 1949. It was discovered in the lab of Selman Waksman, who was later awarded the Nobel Prize in Physiology or Medicine in 1951. Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.
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Product Description
| (2RS,3S,4S,5R)-5-amino-2-(aminomethyl)-6-((2R,3S,4R,5S)-5-((1R,2R,5R,6R)-3,5-diamino-2-((2R,3S,4R,5S)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yloxy)-6-hydroxycyclohexyloxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yloxy)tetrahydro-2H-pyran-3,4-diol |
| Trade names | Neo-rx |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a682274 |
| Pregnancy category |
US: D (Evidence of risk) |
| Legal status | US: ℞-only |
| Routes of administration |
Topical, oral |
| Bioavailability | None |
| Protein binding | N/A |
| Metabolism | N/A |
| Biological half-life | 2 to 3 hours |
| CAS Number | 1404-04-2 |
| ATC code | A01AB08 A07AA01, B05CA09, D06AX04, J01GB05, R02AB01, S01AA03, S02AA07, S03AA01 |
| PubChem | CID: 8378 |
| IUPHAR/BPS | 709 |
| DrugBank | DB00994 |
| ChemSpider | 8075 |
| UNII | I16QD7X297 |
| KEGG | D08260 |
| ChEBI | CHEBI:7508 |
| ChEMBL | CHEMBL449118 |
| Formula | C23H46N6O13 |
| Molecular mass | 614.644 g/mol |
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