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piroxicam-micronized-product

Piroxicam Micronized

Piroxicam /paɪˈrɒksɪˌkæm/ (INN, BAN, USAN, AAN; in some countries it is spelt piroksikam or piroxikam) is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful, inflammatory conditions like arthritis. Piroxicam works by preventing the production of a certain type of body chemical called prostaglandins which are involved in the mediation of pain, stiffness, tenderness and swelling. The medicine is available as capsules, tablets and (not in all countries) as a prescription-free gel 0.5%. It is also available in a betadex formulation, which allows a more rapid absorption of piroxicam from the digestive tract.

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Product Description



4-Hydroxy-2-methyl-N-(2-pyridinyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide


Trade names Feldene and many others[1]
AHFS/Drugs.com monograph
MedlinePlus a684045
Pregnancy category
  • AU: C
  • US: C (Risk not ruled out)
  • D (US), if used during the 3rd trimester, as it may cause ductus arteriosus.
Legal status
  • AU: S4 (Prescription only)
  • CA: ℞-only
  • UK: POM (Prescription only)
  • US: ℞-only
Routes of administration Oral


Protein binding 99%[2]
Metabolism Liver-mediated hydroxylation and glucuronidation[2]
Biological half-life 50 hours[2]
Excretion Urine, faeces


CAS Number 36322-90-4 
ATC code M01AC01 M02AA07, S01BC06
PubChem CID: 5280452
IUPHAR/BPS 7273
DrugBank DB00554 
ChemSpider 10442653 
UNII 13T4O6VMAM 
KEGG D00127 
ChEBI CHEBI:8249 
ChEMBL CHEMBL527 


Formula C15H13N3O4S
Molecular mass 331.348 g/mol

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