Salbutamol, also known as albuterol and marketed as Ventolin among other names, is a medication that opens up the medium and large airways in the lungs. It is used to treat asthma, exercise-induced bronchospasm, and chronic obstructive pulmonary disease (COPD). It may also be used to treat high blood potassium levels. It is usually used by inhaler or nebulizer but is also available as a pill and intravenous solution. Onset of action of the inhaled version is typically within 15 minutes and lasts for two to six hours.
Common side effects include shakiness, headache, fast heart rate, dizziness, and feeling anxious. Serious side effects may include worsening bronchospasm, irregular heartbeat, and low blood potassium levels. While safety is not entirely clear it is likely okay in pregnancy and breastfeeding. Salbutamol is a short-acting β2-adrenergic receptor agonist which works by causing smooth muscles to relax.
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(RS)-4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol |
Trade names | Ventolin, Proventil, others |
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AHFS/Drugs.com | monograph |
Licence data | US FDA:link |
Pregnancy category |
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Legal status |
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Routes of administration | Oral, inhalationa |
Metabolism | Liver |
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Onset of action | <15 min (inhaled), <30 min (pill) |
Biological half-life | 3.8 – 6 hours |
Duration of action | 2 to 8 hrs[2] |
Excretion | Kidney |
CAS Number | 18559-94-9 |
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ATC code | R03AC02 R03CC02 |
PubChem | CID: 2083 |
IUPHAR/BPS | 558 |
DrugBank | DB01001 |
ChemSpider | 1999 |
UNII | QF8SVZ843E |
KEGG | D02147 |
ChEBI | CHEBI:2549 |
ChEMBL | CHEMBL714 |
Formula | C13H21NO3 |
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Molecular mass | 239.311 g/mol |
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