Sucralfate
Sucralfate is a medication primarily taken to treat active duodenal ulcers. Sucralfate is also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.
Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.
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Product Description
| Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum |
| Trade names | Carafate |
|---|---|
| AHFS/Drugs.com | monograph |
| MedlinePlus | a681049 |
| Pregnancy category |
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| Legal status |
|
| Routes of administration | oral, suspension, rectal suspension |
| Bioavailability | 3-5% (local acting) |
|---|---|
| Metabolism | GI; liver: unknown |
| Biological half-life | unknown |
| Excretion | feces, urine |
| CAS Number | 54182-58-0 |
|---|---|
| ATC code | A02BX02 |
| PubChem | CID: 6398525 |
| DrugBank | DB00364 |
| ChemSpider | 4911161 |
| UNII | XX73205DH5 |
| ChEMBL | CHEMBL611727 |
| Formula | C12H54Al16O75S8 |
|---|---|
| Molecular mass | 2086.75 g/mol |
