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FLUMEQUINA BASE

Flumequine[1] is a synthetic fluoroquinolone antibiotic[2][3] used to treat bacterial infections. It is a first-generation fluoroquinolone antibacterial that has been removed from clinical use and is no longer being marketed.[4] It kills bacteria by interfering with the enzymes that cause DNA to unwind and duplicate. Flumequine was used in veterinarian medicine for the treatment of enteric infections (all infections of the intestinal tract),[5] as well as to treat cattle, swine, chickens, and fish, but only in a limited number of countries.[4][6][7] It was occasionally used in France (and a few other European Countries) to treat urinary tract infections under the trade name Apurone.[4][8] However this was a limited indication[9] because only minimal serum levels were achieved.[10]

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Product Description


Systematic (IUPAC) name
7-fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid

AHFS/Drugs.com International Drug Names
Legal status
  • removed from clinical use

Excretion urine and feces

CAS Number 42835-25-6
ATC code J01MB07
PubChem CID: 3374
DrugBank DB08972
ChemSpider 3257
UNII UVG8VSP2SJ
KEGG D02302
ChEBI CHEBI:85267
Synonyms 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]-quinolizine-2-carboxylic acid

Formula C14H12FNO3
Molecular mass 261.25 g/mol
SMILES[show]
InChI[show]

Melting point 253 to 255 °C (487 to 491 °F)

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