Clotrimazol
Clotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.[1] It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system.[2]
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Product Description
| 1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-imidazole |
| Trade names | Lotrimin, Desenex, Canesten |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a682753 |
| Pregnancy category |
AU: A C (oral) and B (topical) (US) |
| Legal status | US: OTC (topical), prescription (oral) |
| Routes of administration |
topical, troche |
| Bioavailability | Poor oral absorption (troche), negligible absorption through intact skin (topical) |
| Protein binding | 90% |
| Metabolism | hepatic |
| Biological half-life | 2 hours |
| CAS Number | 23593-75-1 |
| ATC code | A01AB18 D01AC01 G01AF02 QJ02AB90 |
| PubChem | CID: 2812 |
| IUPHAR/BPS | 2330 |
| DrugBank | DB00257 |
| ChemSpider | 2710 |
| UNII | G07GZ97H65 |
| KEGG | D00282 |
| ChEBI | CHEBI:3764 |
| ChEMBL | CHEMBL104 |
| Formula | C22H17ClN2 |
| Molecular mass | 344.837 g/mol |
| SMILES[show] | |
| InChI[show] | |
