Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand names Cardura and Carduran, is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia (BPH).
Starting at
(RS)-2-[4-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine |
Trade names | Cardura |
AHFS/Drugs.com | monograph |
MedlinePlus | a693045 |
Legal status | ℞ (Prescription only) |
Routes of administration |
oral |
Bioavailability | 65% |
Protein binding | 98% |
Metabolism | Hepatic |
Biological half-life | 22 hours |
CAS Number | 74191-85-8 |
ATC code | C02CA04 |
PubChem | CID: 3157 |
IUPHAR/BPS | 7170 |
DrugBank | DB00590 |
ChemSpider | 3045 |
UNII | NW1291F1W8 |
KEGG | D07874 |
ChEBI | CHEBI:4708 |
ChEMBL | CHEMBL707 |
Formula | C23H25N5O5 |
Molecular mass | 451.475 g/mol |
SMILES[show] | |
InChI[show] |