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doxycycline-hyclate

Doxycycline Hyclate

Doxycycline is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. It is useful for bacterial pneumonia, acne, chlamydia infections, early Lyme disease, cholera and syphilis. It is also useful for the treatment of malaria when used with quinine and for the prevention of malaria. Doxycycline can be used either by mouth or intravenously.[1]

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Product Description


(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)- 3,5,10,12,12a-pentahydroxy- 6-methyl- 1,11-dioxo- 1,4,4a,5,5a,6,11,12a-octahydrotetracene- 2-carboxamide

Pronunciation /ˌdɒksiˈsaɪklin/
Trade names Doryx, Doxyhexal, Doxylin among others
AHFS/Drugs.com monograph
MedlinePlus a682063
Licence data US FDA:link
Pregnancy
category
AU: D
US: D (Evidence of risk)
Legal status AU: S4 (Prescription only)
UK: POM (Prescription only)
US: ℞-only
Routes of
administration
by mouth, intravenous[1]

Bioavailability 100%
Protein binding 90%
Metabolism Hepatic
Biological half-life 15–25 hours
Excretion Urine (40%)

CAS Number 564-25-0
ATC code J01AA02 A01AB22
PubChem CID: 11256
DrugBank DB00254
ChemSpider 10482106
UNII 334895S862
KEGG D00307
ChEBI CHEBI:60648
ChEMBL CHEMBL1433

Formula C22H24N2O8
Molecular mass 444.43 g/mol
SMILES[show]
InChI[show]