Serine (abbreviated as Ser or S)[3] encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+
3 form under biological conditions), a carboxyl group (which is in the deprotonated –COO−
form under biological conditions), and a side chain hydroxyl group, classifying it as a polar amino acid. It is non-essential in humans, meaning the body can synthesize it.
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IUPAC name
Serine
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Other names
2-Amino-3-hydroxypropanoic acid
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CAS Number
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56-45-1 (L-isomer) 302-84-1 312-84-5 (D-isomer) |
ChEBI | CHEBI:17115 |
ChEMBL | ChEMBL11298 |
ChemSpider | 5736 (L-form) 597 |
DrugBank | DB00133 |
EC Number | 206-130-6 |
IUPHAR/BPS
|
726 |
Jmol interactive 3D | Image |
PubChem | 617 |
UNII | 452VLY9402 |
InChI[show]
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SMILES[show]
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Chemical formula
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C3H7NO3 |
Molar mass | 105.09 g·mol−1 |
Appearance | white crystals or powder |
Density | 1.603 g/cm3 (22 °C) |
Melting point | 246 °C (475 °F; 519 K) decomposes |
Solubility in water
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soluble |
Acidity (pKa) | 2.21 (carboxyl), 9.15 (amino)[1] |
Structure and
properties |
Refractive index (n), Dielectric constant (εr), etc. |
Thermodynamic
data |
Phase behaviour solid–liquid–gas |
Spectral data
|
UV, IR, NMR, MS |