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l-threonine

L-Threonine

Threonine (abbreviated as Thr or T) encoded by the codons ACU, ACC, ACA, and ACG is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated -+NH3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated –COO- form under biological conditions), and an alcohol containing side chain, classifying it as a polar, uncharged(at physiological pH) amino acid. It is essential in humans, meaning the body cannot synthesize it, and must be ingested in our diet. Isoleucine is synthesized from aspartate in bacterial cells such as E. coli.[2]

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Product Description


IUPAC name

Threonine
Other names

2-Amino-3-hydroxybutanoic acid

CAS Number
80-68-2
72-19-5 (L-isomer)
ChEBI CHEBI:57926
ChEMBL ChEMBL291747
ChemSpider 6051
DrugBank DB00156
EC Number 201-300-6
IUPHAR/BPS
4785
Jmol interactive 3D Image
PubChem 6288
UNII 2ZD004190S
InChI[show]
SMILES[show]

Chemical formula
C4H9NO3
Molar mass 119.12 g·mol−1
Solubility in water
(H2O, g/dl) 10.6(30°),14.1(52°),19.0(61°)
Acidity (pKa) 2.63 (carboxyl), 10.43 (amino)[1]

Structure and
properties
Refractive index (n),
Dielectric constant (εr), etc.
Thermodynamic
data
Phase behaviour
solid–liquid–gas
Spectral data
UV, IR, NMR, MS