Mebendazole
Mebendazole (MBZ) is a medication used to treat a number of parasitic worm infestations.[2] This includes ascariasis, pinworm disease, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others.[2] It is taken by mouth.[2]
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Product Description
| methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate |
| Trade names | Vermox[1] |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a682315 |
| Pregnancy category |
AU: B3 US: C (Risk not ruled out) |
| Legal status |
AU: S2 (Pharmacy only) CA: OTC UK: General sales list (GSL, OTC) US: ℞-only |
| Routes of administration |
Oral |
| Bioavailability | 2-10% |
| Protein binding | 95% |
| Metabolism | Hepatic (extensive) |
| Biological half-life | 3-6 hours |
| Excretion | Faeces, urine (5-10%) |
| CAS Number | 31431-39-7 |
| ATC code | P02CA01 QP52AC09 |
| PubChem | CID: 4030 |
| DrugBank | DB00643 |
| ChemSpider | 3890 |
| UNII | 81G6I5V05I |
| KEGG | D00368 |
| ChEBI | CHEBI:6704 |
| ChEMBL | CHEMBL685 |
| Formula | C16H13N3O3 |
| Molecular mass | 295.293 g/mol |
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| Melting point | 288.5 °C (551.3 °F) |
