Spectinomycin , sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle.
Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class and works by stopping the making of protein by certain bacteria.
Spectinomycin was discovered 1961. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost is about 5 US dollar per dose. It is not available in the United States. It is made from the bacterium Streptomyces spectabilis.
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(1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one |
Trade names | Trobicin |
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AHFS/Drugs.com | monograph |
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CAS Number | 1695-77-8 |
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ATC code | J01XX04 |
PubChem | CID: 15541 |
DrugBank | DB00919 |
ChemSpider | 14785 |
UNII | 93AKI1U6QF |
KEGG | D08526 |
ChEBI | CHEBI:9215 |
ChEMBL | CHEMBL1167 |
Synonyms | (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one |
Formula | C14H24N2O7 |
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Molecular mass | 332.35 g/mol |
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