Biotin, also known as vitamin H or coenzyme R,[2] is a water-soluble B-vitamin (vitamin B7).
It is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
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IUPAC name
5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
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Other names
Vitamin B7; Vitamin H; Coenzyme R; Biopeiderm
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CAS Number
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58-85-5 |
ChEBI | CHEBI:15956 |
ChEMBL | ChEMBL857 |
ChemSpider | 149962 |
DrugBank | DB00121 |
IUPHAR/BPS
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4787 |
Jmol interactive 3D | Image Image |
KEGG | D00029 |
PubChem | 171548 |
UNII | 6SO6U10H04 |
InChI[show]
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SMILES[show]
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Chemical formula
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C10H16N2O3S |
Molar mass | 244.31 g·mol−1 |
Appearance | White crystalline needles |
Melting point | 232 to 233 °C (450 to 451 °F; 505 to 506 K) |
Solubility in water
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22 mg/100 mL |
ATC code | A11HA05 |
NFPA 704 |