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TRIMETOPRIMA LACTATO
La trimetoprima es un antibiótico bacteriostático derivado de la trimetoxibenzilpirimidina y de uso casi exclusivo en el tratamiento de infecciones urinarias.1
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Product Description
| 5-(3,4,5-trimetoxibenzil)pirimidin-2,4-diamina |
| Número CAS | 738-70-5 | |
| Código ATC | J01EA01 | |
| PubChem | 5578 | |
| DrugBank | DB00440 | |
| UNII | AN164J8Y0X | |
| KEGG | D00145 | |
| ChEBI | 9731 | |
| Fórmula | C14H18N4O3 | |
| Peso mol. | 290,32 | |
| SMILES[mostrar] | ||
| InChI[mostrar] | ||
| Sinónimos | 2,4-diamino-5-(3,4,5-trimetoxibenzil)pirimidina | |
| P. de fusión | 199-203 °C (-134 °F) | |
| Solubilidad en agua | 12,1 mg/mL (20 °C) | |
| Biodisponibilidad | 90–100% | |
|---|---|---|
| Unión proteica | 42-46% | |
| Metabolismo | Hepático | |
| Vida media | 8–11 horas | |
| Excreción | Renal 50–60% | |
| Nombre comercial | Bactrim. Septra | |
|---|---|---|
| Cat. embarazo | B3 (AU) C (EUA) | |
| Estado legal | S4 (AU) POM (UK) | |
| Vías de adm. | oral | |
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