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Azithromycin_structure

Azithromycin Dihidrate

Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections.[2] This includes middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain other intestinal infections. It may also be used for a number of sexually transmitted infections including chlamydia and gonorrhea infections. Along with other medications, it may also be used for malaria. It can be taken by mouth or intravenously with doses once per day.[2]

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Product Description


(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo- 11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadec-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside

Trade names Zithromax, Azithrocin, others[1]
AHFS/Drugs.com monograph
MedlinePlus a697037
Licence data US FDA:link
Pregnancy
category
AU: B1
US>: B (No risk in non-human studies)
Legal status US: ℞-only
Routes of
administration
Oral (capsule, tablet or suspension), intravenous, ophthalmic

Bioavailability 38% for 250 mg capsules
Metabolism Hepatic
Biological half-life

11–14 h (single dose)

68 h (multiple dosing)

Excretion Biliary, renal (4.5%)

CAS Number 83905-01-5
ATC code J01FA10 S01AA26
PubChem CID: 55185
IUPHAR/BPS 6510
DrugBank DB00207
ChemSpider 10482163
UNII J2KLZ20U1M
KEGG D07486
ChEBI CHEBI:2955
ChEMBL CHEMBL529
NIAID ChemDB 007311
Synonyms 9-deoxy-9a-aza-9a-methyl-9a-homoerythromycin A

Formula C38H72N2O12
Molecular mass 748.984 g·mol−1
SMILES[show]
InChI[show]