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leucine

L-Leucine

Leucine (abbreviated as Leu or L; encoded by the six codons UUA, UUG, CUU, CUC, CUA, and CUG) is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated -+NH3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated –COO- form under biological conditions), and an isobutyl side chain, classifying it as a nonpolar (at physiological pH) amino acid. It is essential in humans, meaning the body cannot synthesize it and thus it must be obtained from the diet.

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Product Description


IUPAC name

Leucine
Other names

2-Amino-4-methylpentanoic acid

CAS Number
61-90-5
ChEBI CHEBI:57427
ChEMBL ChEMBL291962
ChemSpider 5880
DrugBank DB01746
IUPHAR/BPS
3312
Jmol interactive 3D Image
KEGG D00030
PubChem 6106
UNII GMW67QNF9C
InChI[show]
SMILES[show]

Chemical formula
C6H13NO2
Molar mass 131.18 g·mol−1
Acidity (pKa) 2.36 (carboxyl), 9.60 (amino)[1]

Structure and
properties
Refractive index (n),
Dielectric constant (εr), etc.
Thermodynamic
data
Phase behaviour
solid–liquid–gas
Spectral data
UV, IR, NMR, MS