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Dicloxacillin

DICLOXACILLIN SODICA POLVO

Dicloxacillin (INN) is a narrow-spectrum β-Lactam antibiotic of the penicillin class.[1] It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria.[1] It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. Dicloxacillin is available under a variety of trade names including Diclocil (BMS).[2]

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Product Description


(2S,5R,6R)-6-{[3-(2,6-dichlorophenyl)-5-methyl-
oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-
1-azabicyclo[3.2.0]heptane-2-carboxylic acid

AHFS/Drugs.com monograph
MedlinePlus a685017
Pregnancy
category
AU: B2
US: B (No risk in non-human studies)
Legal status AU: S4 (Prescription only)
US: ℞-only
Routes of
administration
Oral

Bioavailability 60 to 80%
Protein binding 98%
Metabolism Hepatic
Biological half-life 0.7 hours
Excretion Renal and biliary

CAS Number 3116-76-5
ATC code J01CF01 QJ51CF01
PubChem CID: 18381
DrugBank DB00485
ChemSpider 17358
UNII COF19H7WBK
KEGG D02348
ChEBI CHEBI:4511
ChEMBL CHEMBL893

Formula C19H17Cl2N3O5S
Molecular mass 470.327 g/mol
SMILES[show]
InChI[show]

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