Dicloxacillin (INN) is a narrow-spectrum β-Lactam antibiotic of the penicillin class.[1] It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria.[1] It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. Dicloxacillin is available under a variety of trade names including Diclocil (BMS).[2]
Starting at
(2S,5R,6R)-6-{[3-(2,6-dichlorophenyl)-5-methyl-
oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia- 1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
AHFS/Drugs.com | monograph |
MedlinePlus | a685017 |
Pregnancy category |
AU: B2 US: B (No risk in non-human studies) |
Legal status |
AU: S4 (Prescription only) US: ℞-only |
Routes of administration |
Oral |
Bioavailability | 60 to 80% |
Protein binding | 98% |
Metabolism | Hepatic |
Biological half-life | 0.7 hours |
Excretion | Renal and biliary |
CAS Number | 3116-76-5 |
ATC code | J01CF01 QJ51CF01 |
PubChem | CID: 18381 |
DrugBank | DB00485 |
ChemSpider | 17358 |
UNII | COF19H7WBK |
KEGG | D02348 |
ChEBI | CHEBI:4511 |
ChEMBL | CHEMBL893 |
Formula | C19H17Cl2N3O5S |
Molecular mass | 470.327 g/mol |
SMILES[show] | |
InChI[show] |
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