Pheniramine (INN, trade name Avil, among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.
Starting at
N,N-dimethyl-3-phenyl-3-pyridin-2-yl-propan-1-amine |
AHFS/Drugs.com | International Drug Names |
MedlinePlus | a606008 |
Pregnancy category |
AU: A US: C (Risk not ruled out) |
Routes of administration |
Oral ; injection (intramuscular or slow intravenous); topical (ophthalmic/nasal solution) |
Metabolism | Hepatic hydroxylation, demethylation and glucuronidation |
Excretion | Renal |
CAS Number | 86-21-5 |
ATC code | D04AA16 R06AB05 |
PubChem | CID: 4761 |
IUPHAR/BPS | 7267 |
DrugBank | DB01620 |
ChemSpider | 4597 |
UNII | 134FM9ZZ6M |
KEGG | D08355 |
ChEMBL | CHEMBL1193 |
Formula | C16H20N2 |
Molecular mass | 240.343 g/mol |
SMILES[show] | |
InChI[show] |
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