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meclizine-hcl

MECLIZINA HCL

Meclizine (INN,[1] or meclozine) is an antihistamine considered to be an antiemetic. It is sold under the brand names Bonine, Bonamine, Antivert, Postafen, Sea Legs, and Dramamine II (Less Drowsy Formulation). Emesafene is a combination of meclizine (1/3) and pyridoxine (2/3). In Canada, Antivert Tab (which is no longer available) was a combination of meclizine and nicotinic acid.[2]

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Product Description


(RS)-1-[(4-chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine

MedlinePlus a682548
Pregnancy
category
US: B (No risk in non-human studies)
Legal status AU: S4 (Prescription only)
CA: OTC
US: OTC
Routes of
administration
Oral, sublingual/buccal

Metabolism hepatic
Biological half-life 6 hours

CAS Number 569-65-3
ATC code R06AE05
PubChem CID: 4034
IUPHAR/BPS 2757
DrugBank DB00737
ChemSpider 3894
UNII 3L5TQ84570
ChEMBL CHEMBL1623

Formula C25H27ClN2
Molecular mass 390.948 g/mol

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InChI[show]

Boiling point 230 °C (446 °F)

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