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enrofloxacin-base

ENROFLOXACINA BASE

Enrofloxacin (ENR) is a fluoroquinolone antibiotic sold by the Bayer Corporation under the trade name Baytril. Enrofloxacin is currently approved by the FDA for the treatment of individual pets and domestic animals in the United States. In September 2005, the FDA withdrew approval of Baytril for use in water to treat flocks of poultry, as this practice was noted to promote the evolution of fluoroquinolone-resistant strains of the bacterium Campylobacter, a human pathogen.[4]

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Product Description


1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

AHFS/Drugs.com International Drug Names
Pregnancy
category
AU: B3
US: C (Risk not ruled out)
Legal status AU: S4 (Prescription only)
UK: POM (Prescription only)
Routes of
administration
Oral, subcutaneous injection, topical (ear drops)

Bioavailability 80% in dogs, 65-75% in sheep [1]
Metabolism Renal and non-renal[2]
Biological half-life 4–5 hours in dogs, 6 hours in cats, 1.5 – 4.5 hours in sheep.
Excretion Bile (70%); Renal (30%)[3]

CAS Number 93106-60-6
ATCvet code QJ01MA90
PubChem CID: 71188
ChemSpider 64326
UNII 3DX3XEK1BN
KEGG D02473
ChEBI CHEBI:35720
ChEMBL CHEMBL15511

Formula C19H22FN3O3
Molecular mass 359.4
SMILES[show]
InChI[show]

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