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methocarbamol

METOCARBAMOL

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. Under the trade name Robax, it is marketed by Actient Pharmaceuticals in the United States and Pfizer in Canada. The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase.[2] The muscle relaxant effects of methocarbamol are largely attributed to central depressant effects;[3] however, peripheral effects of methocarbamol to prolong muscle refractory period have also been reported.[4]

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Product Description


(RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl

AHFS/Drugs.com monograph
MedlinePlus a682579
Pregnancy
category

AU: B2
US: C (Risk not ruled out)

Legal status CA: OTC
US: ℞-only
Routes of
administration
Oral, intravenous

Metabolism Hepatic
Biological half-life 1.14–1.24 hours[1]

CAS Number 532-03-6
ATC code M03BA03
PubChem CID: 4107
IUPHAR/BPS 6829
DrugBank DB00423
ChemSpider 3964
UNII 125OD7737X
KEGG D00402
ChEBI CHEBI:6832
ChEMBL CHEMBL1201117

Formula C11H15NO5
Molecular mass 241.241 g/mol

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